200 years after his shocking creation, Dr. Frankenstein’s creature, Adam, still walks the earth. But when he finds himself in the middle of a war over the fate of humanity, Adam discovers he holds the key that could destroy humankind.

After a group of biologists discovers a huge network of unexplored caves in Romania and, believing it to be an undisturbed eco-system that has produced a new species, they hire the best American team of underwater cave explorers in the world. While exploring deeper into the underwater caves, a rockslide blocks their exit, and they soon discover a larger carnivorous creature has added them to its food chain.