Mystery Girls follows two former detective TV show starlets brought back together by a real-life mystery. Charlie Contour is a suburban housewife and mother, while Holly Hamilton longs for her glory days in the 90’s when she was on television. Both of their lives are disrupted when Nick, a witness to a crime and a ‘Mystery Girls’ fanatic, will only speak to the infamous duo, and the former friends must reunite and put their TV crime-solving skills to the test.

Stef Foster, a dedicated police officer, and her partner Lena Adams, a school vice principal, have built a close-knit, loving family with Stef’s biological son from a previous marriage, Brandon, and their adopted twins, Mariana and Jesus. Their lives are disrupted in unexpected ways when Lena meets Callie, a hardened teen with an abusive past who has spent her life in and out of foster homes. Lena and Stef welcome Callie and her brother, Jude, into their home thinking it’s just for a few weeks, until a more permanent placement can be found. But life has something else in store for the Fosters.

A young woman is recruited into a secret government agency to be “stitched” into the minds of the recently deceased, using their memories to investigate murders.