After proving himself on the field of battle in the French and Indian War, Benjamin Martin wants nothing more to do with such things, preferring the simple life of a farmer. But when his son Gabriel enlists in the army to defend their new nation, America, against the British, Benjamin reluctantly returns to his old life to protect his son.

The residents of a rural mining town discover that an unfortunate chemical spill has caused hundreds of little spiders to mutate overnight to the size of SUVs. It’s then up to mining engineer Chris McCormack and Sheriff Sam Parker to mobilize an eclectic group of townspeople, including the Sheriff’s young son, Mike, her daughter, Ashley, and paranoid radio announcer Harlan, into battle against the bloodthirsty eight-legged beasts.