A newly married couple discovers disturbing, ghostly images in photographs they develop after a tragic accident. Fearing the manifestations may be connected, they investigate and learn that some mysteries are better left unsolved.

Following the events of Ju-on: The Beginning of the End, Mai, the older sister of elementary schoolteacher Yui Shono, goes to look for her sister, who disappeared after a year while working in an elementary school. Mai soon discovers the Teriyaki household who tells her about what happened to her sister. Mai will now uncover the dark secrets of Ju-on and will try to end the curse once and for all.

Infection takes place in a dark, isolated hospital, where one doctors mistake has led to dire consequences for a patient. In a hospital death is just a breath away.

An elementary school teacher named Yui visits the home of a boy named Toshio Saeki who’s been absent from school for a long period of time. When she arrives, she re-lives the horrifying events that occurred in the Saeki household 10 years earlier.