Warriors called “Saints” are the champions of hope who have always appeared since the Age of Myth whenever evil threatens the world. In this present day story, many years since the long fought “Holy War” we find Saori Kido, a girl troubled by her mysterious powers. She is saved by a boy, Seiya “Bronze Saint” from a sudden attack by an assassin, through the accident Saori realizes her destiny and mission and decides to go to “Sanctuary” with Seiya and his company of Bronze Saints. In Sanctuary they confront “Pope” and wage a desperate battle against the greatest Saints, the “Gold Saints”.

Set in the year 2020, Shiori Genbo (Ayame Gouriki) runs the large corporation Funtom. Shiori is also a descendant of prestigious noble family Phantomhive of England. As a descendant of the noble family Phantomhive, Shiori solves difficult cases which are ordered by the queen. In order to take revenge, Shiori makes a deal with Butler Sebastian (Hiro Mizushima). Their deal involves Butler Sebastian protecting Shiori until her revenge is fulfilled and then Sebastian will consume her spirit.

Somewhere in Tokyo, there is a room. In that room is a black sphere. Periodically, people who should otherwise have died are transferred to the room. There, the sphere gives them special suits and weapons, and sends them out on a mission to kill aliens here on Earth. While these missions take place, the rest of the world is largely oblivious to them. These missions are lethal – few participants survive them. The sphere calls the shots, and it’s not the slightest bit nice. Its name… Gantz.