Lionel Essrog, a private detective living with Tourette syndrome, ventures to solve the murder of his mentor and best friend — a mystery that carries him from the gin-soaked jazz clubs of Harlem to the slums of Brooklyn to the gilded halls of New York’s power brokers.

Best friends since they were kids, Rabbi Jacob Schram and Father Brian Finn are dynamic and popular young men living and working on New York’s Upper West Side. When Anna Reilly, once their childhood friend and now grown into a beautiful corporate executive, suddenly returns to the city, she reenters Jake and Brian’s lives and hearts with a vengeance. Sparks fly and an unusual and complicated love triangle ensues.