A real life account of the deadly Nipah virus outbreak in Kerala, and the courageous fight put on by several individuals which helped to contain the epidemic.

Padmini (Manju Warrier) a traditional married woman who goes to Manali, Himachal Pradesh to meet her car rallyist husband Giri (Jinu Joseph). Rani a North Indian bred troublemaker with feminine qualities running away from a rowdy who has posed threat to her life. As fate would have, they meet together and an illustrious journey starts where they are met with pleasantness, happiness, dread and excitement.