This scripted anthology series mashes up wildly different genres to tell suspenseful stories with funny, imaginative twists. Each episode turns familiar tropes inside out to create a curated and eclectic collection of stories filled with equal parts nostalgia and modern satire.

Karen Best has a big life. She’s a big girl with a big personality and a big love of Chardonnay, which occasionally, causes her to make some big mistakes with men. But the biggest thing about Karen is her big heart, a heart she uses to excel at her job as a counselor at a group home for young adults with Down syndrome located in an old brownstone in New York City.