Ana, a young Spanish woman who has just been dumped by her boyfriend, and her brother Tono, receive a call from their father to tell him that he is getting married in Mexico to a woman he met on the Internet. When they get there, they discover that the girl is 30 years younger than her father and they begin to live with her new in-laws, with the inevitable cultural clashes that this will entail.

Laura has been with Antonio all her life and, just when she begins to wonder if that is really the life she wants, Sergio and Siena cross paths in their lives. Sergio is a former high school classmate and Siena, his millennial girlfriend who arrives to revolutionize everyone’s lives. Laura, Raquel and Cris, close friends for years, convince their respective husbands to play a game that Siena proposes to them: the game of keys. The game consists of everyone putting their keys in a bowl. At random, each one chooses some keys and he must go to spend the night with the owner of the keys. This game will revolutionize the group of friends and their lives. It will make them discover who they are and what they really want.

Flora and Victor are fun, modern, caring parents. That is, until they decide to get a divorce, and the perfect job opportunity turns up for them. They now have one problem: custody.

Pedro, Arturo and Eligio are three college professors who lost their job because of economic crisis. Accidentally they find a solution for all of their problems; a multi-vitamin that allows them to party all night long without any side effects. The three professors will be launched into the world of nightclubs and the shady business, in order to market the merchandise. Of course, it seems that they are not as prepared for it as they thought.

A dysfunctional group of wannabe Basque terrorists awaits word about a new mission while Spain makes a run at the World Cup title.