In a pagan Estonian village where werewolves, the plague, and spirits roam, the villagers’ main problem is how to survive the cold, dark winter. And, to that aim, nothing is taboo. People steal from each other, from their German manor lords, and from spirits, the devil, and Christ. Amongst the disorder, a young farm girl hopelessly and forlornly in love with a village boy.

During a stopover in Germany in the middle of a carefree road trip through Europe, two American girls find themselves alone at night when their car breaks down in the woods. Searching for help at a nearby villa, they are wooed into the clutches of a deranged retired surgeon who explains his mad scientific vision to his captives’ utter horror. They are to be the subjects of his sick lifetime fantasy: to be the first to connect people, one to the next, and in doing so bring to life “the human centipede.”

Taking inspiration from The Human Centipede films, the warden of a notorious and troubled prison looks to create a 500-person human centipede as a solution to his problems.