Neighborhood best friends and urban millennials Dan and Kevin hilariously climb the ladder to nowhere in Flatbush, Brooklyn. But even inside the losing, they find there are little wins that come from tackling hipsters, mental health issues and the rising tide of gentrification.

Alienated in politically-ambiguous Moscow, young woman deals with severe OCD, while her cousin in Berlin tries to build a romantic relationship ignoring her own condition. In a parallel New York City realm, a heartbroken boxer struggles with addiction, self worth and online anxiety, which connects all the heroes from a universal level.