Catherine Black is a world-famous neurologist at the state-of-the-art medical institution known as “The Cube”. Catherine is brilliant, beautiful, and at the top of her game, though she’s hiding a secret of her own: she’s bipolar. Each week, the doctors on staff attempt to unravel the mysteries of the brain and are constantly challenged by cases never-before-seen on television. The medical stories are moving, bizarre and a visual feast. The personal stories are riveting. The patients have rare, highly visual, often hallucinogenic and startling conditions, which we’ll see through their eyes as Catherine diagnoses and treats them.

A vast international plot explodes when a beautiful Jane Doe is discovered naked in Times Square, completely covered in mysterious, intricate tattoos with no memory of who she is or how she got there. But there’s one tattoo that is impossible to miss: the name of FBI agent Kurt Weller, emblazoned across her back. “Jane,” Agent Weller and the rest of the FBI quickly realize that each mark on her body is a crime to solve, leading them closer to the truth about her identity and the mysteries to be revealed.