The rivalries, romances, hopes and fears of the residents of the fictional Midwestern metropolis, Genoa City. The lives and loves of a wide variety of characters mingle through the generations, dominated by the Newman, Abbott, Baldwin and Winters families.

In the early 1970s, Dr. Henry West creates an institute to find people with supernatural abilities. When Judith Winstead comes to the facility, she exhibits amazing abilities that the military wants to turn into a weapon.

Alex Whitman (Matthew Perry) is a designer from New York City who is sent to Las Vegas to supervise the construction of a nightclub that his firm has been hired to build. Alex is a straight-laced WASP-ish type who, while enjoying a night on the town, meets Isabel Fuentes (Salma Hayek), a free-spirited Mexican-American photographer. Alex and Isabel are overtaken by lust at first sight and end up sp