A shipwreck victim (John Loder) washes up on a homicidal big-game hunter’s (Edgar Barrier) Caribbean island.

Sketch artist Irena Dubrovna (Simone Simon) and American architect Oliver Reed (Kent Smith) fall in love and marry after a brief courtship. But Irena believes that she suffers from an ancient curse and won’t consummate the union for fear that she will turn into a panther compelled to kill her lover.