4400 centers on the return of 4400 people who, previously presumed dead or reported missing, reappear on Earth. Though they have not aged physically, some of them seem to have deeper alterations ranging from superhuman strength to an unexplained healing touch. A government agency is formed to track the 4400 people after one of them commits a murder.

When an engaged couple can’t agree on anything, the mother of the groom (Linda Gray) hires a wedding planner (Danica McKellar) and an event planner (Paul Greene) to help put together the wedding of their dreams. The two planners are as different as night and day, but as they too learn to compromise, they discover opposites do indeed attract and can combine to produce incredible results!